Licensing Opportunity – Next-Generation CAR-T for Multiple Myeloma
This enhanced BCMA-targeting CAR-T technology co-expresses a granzyme B–NOXA fusion protein, overcoming resistance in multiple myeloma by directly neutralizing MCL-1–mediated survival mechanisms.
Improved tumor killing in vitro & in vivo
Selective targeting of malignant cells
Compatible with current CAR-T platforms, including in vivo engineering strategies
Read the publication in Nature Communications:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12089368/
Patent application upon request
We are actively seeking industry partners for licensing and development.
Contact Danielle Counotte to explore this opportunity.
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Utrecht Holdings
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Heidelberglaan 8
3584 CS Utrecht
The Netherlands
BTW-nummers (VAT numbers): UU Holding BV: NL806771604B01 || UMCU Holding BV: NL806125214B01